Patients and methods from a singleinstitution registry of 527 consecutive. Fifth ovarian cancer consensus conference of the gynecologic cancer intergroup. Preparation of the leuven consensus meeting all testing prespecified subgroups. Pdf 2004 consensus statements on the management of ovarian. There is no evidence to support adjuvant treatment, and survival is excellent 4 x 4 ledermann, j. Endometrial cancer is the most common gynecologic malignancy in women worldwide.
Abstract since the early 1970s, the world health organization and the international federation of gynecology and obstetrics have classified borderline ovarian tumors as an independent group of ovarian epithelial tumors. Baden, germany, in september 2004, which was organized by the gynecological cancer intergroup. Hensley ml, barrette ba, baumann k, gaffney d, hamilton al, kim jw et al. However, uterine serous carcinoma usc represents an aggressive histologic subtype of endometrial cancer. Epithelial ovarian cancer generally presents at an advanced stage and is the most common cause of gynaecological cancer death. Final document of the 3rd international gynecologic cancer intergroup ovarian cancer consensus conference gcig occc 2004. Initial therapy includes surgery and adjuvant therapy. Fortunately, for patients with figo stage ia disease, observation alone is sufficient. For ovarian cancer, successful international consensus meetings have been organized, and the most important was the meeting in baden. Abstract clear cell carcinoma of the ovary ccc is a histologic subtype of epithelial ovarian cancer with a distinct clinical behavior.
Gynecologic cancer intergroup gcig international journal of. Gynecologic cancer intergroup an organization of international cooperative groups for clinical trials in gynecologic cancers. Fujiwara h, yokota h, monk b, treilleux i, devouassouxshisheboran m, davis a et al. Smallcell carcinoma of the uterine cervix is a rare and aggressive tumor, and the prognosis is poor compared with those of squamous cell carcinoma and adenocarcinoma of the uterine cervix, even wh. Fifth ovarian cancer consensus conference of the gynecologic cancer intergroup gcig. Purpose the aim of the study was to compare the prognostic value of a response by the gynecologic cancer intergroup gcig cancer antigen ca 125 response criteria and the response evaluation criteria in solid tumors recist on survival in patients with ovarian carcinoma receiving secondline chemotherapy. Populationbased screening has been ineffective, but new approaches for early diagnosis and prevention that leverage molecular genomics are in development. Harmonising clinical trials within the gynecologic cancer. With the overall goal of creating a roadmap to improve translational design for future gynecological cancer trials and of defining translational goals, a main discussion was held during a brainstorming day of the gynecologic cancer intergroup gcig translational research committee and overall conclusions are here reported. Its statements still are valid and are applied in daily routine. Evaluation of new platinumbased treatment regimens in. There are marked geographic differences in the prevalence of ccc. This manuscript provides a summary of the topics discussed during the gynecologic cancer intergroup gcig translational research brainstorming day and provides an overview of the consensus process together with ongoing questionsproblems that remain to be addressed. The gynecologic cancer intergroup gcig is a collaborative group conceived in 1993 and formalized in 1997 with agreed upon statutessops.
The gynecologic cancer intergroup gcig fifth ovarian cancer consensus conference occc was held in tokyo, japan from 7 to 9 november 2015. Up to 90% ovarian carcinosarcomas ocs will have disease that has spread beyond the ovary. Article gynecologic cancer intergroup gcig consensus. The fifth ovarian cancer consensus conference occc of the gynecologic cancer intergroup gcig held in tokyo in november 2015 gathered representatives from 29 collaborative research groups to propose international consensus statements on designing new. Reed nsi, gomezgarcia e, gallardorincon d, barrette b, baumann k, friedlander m et al. Edgar petru, austria, gynecologic cancer intergroup gcig. The gynecologic cancer intergroup gcig fifth ovarian cancer consensus conference occc was held in tokyo, japan from 7 to 9. This report provides the outcomes from the fourth ovarian cancer consensus conference. Should ca125 response criteria be preferred to response. Outcomes tend to be worse compared with cutaneous melanomas likely because of the later presentation and physical biological characteristics of these tumors. International journal of gynecological cancer, 21 4, 750755. Gynecologic cancer intergroup, ovarian cancer consensus conference. The gynecologic cancer intergroup gcig fifth ovarian cancer consensus conference. Ochiai k, on behalf of the participants of the 5th ovarian cancer consensus conference.
This consensus document was presented at the tnm uicc core group meeting in geneva at the beginning of may 2008, where it was. Fifth ovarian cancer consensus conference of the gynecologic. This is a precopyedited, authorproduced version of an article accepted for publication in annals. The survival of women with advanced uc or oc is worse than survival of endometrioid or highgrade serous histologies. As highlighted in the consensus statements of the second workshop on advanced ovarian cancer, a network of national or international groups might potentially. Results of the 2006 innsbruck international consensus. The 4th ovarian cancer consensus conference was held in vancouver, canada, in june 2010, and the resulting publications herein provide an invaluable resource to researchers in the. Smallcell carcinoma of the uterine cervix discovered with. Most endometrial cancers present as earlystage disease, with a 5year survival rate of greater than 85%. It is a collaborative network consisting of appointed representatives from international and national research groups performing clinical trials in gynecologic cancers. Progressionfree survival of patients with figo stage i cancer n 209, stratified by adjuvant therapy. Jaime prat, spain, international society of gynecological pathologists isgyp. Revised figo staging for carcinoma of the vulva, cervix.
Stuart gc, kitchener h, bacon m, dubois a, friedlander m, ledermann j, et al. Report from the fourth ovarian cancer consensus conference. It is reasonable to follow already established guidelines from other professional groups and societies. The ccc is more likely to be detected at an early stage than highgrade serous cancers, and when confined within the ovary, the prognosis is good. Amant f1, floquet a, friedlander m, kristensen g, mahner s, nam ej, powell ma, raycoquard i, siddiqui n, sykes p, westermann am, seddon b. Prognosis for localized stage disease is poor with a high risk of recurrences, both local and distant, occurring within 1 year. Most treatment decisions are based on extrapolation from data regarding cutaneous melanomas of other sites. It provided international consensus on 15 important questions in 4 topic areas, which were generated in accordance with the mission statement to establish international consensus for designing better clinical trials.
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